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International Journal of
Pharmaceutical Science and Research
ARCHIVES
VOL. 11, ISSUE 1 (2026)
Composition determined by IR spectroscopy of chloroform
Authors
Ioana Stanciu
Abstract

In this article, we determined the composition of chloroform by FTIR spectroscopy using a Perkin Elmer Spectrum GX spectrometer. Chloroform contains absorption bands between 1312 and 757cm-1 and contains the following functional groups: —COO, —CONH, C-H and CHCl3. Chloroform (trichloromethane, CHCl) is a halogenated organic compound, belonging to the class of chloromethanes, characterized by a molecular structure formed by a carbon atom bonded to a hydrogen atom and three chlorine atoms. This electronic distribution gives the molecule relative stability, low polarity and high volatility, properties that have determined its historical uses in extraction, laboratory and medicine. Currently, its role is being reevaluated due to toxicological risks, potential carcinogenicity and bacterial formation of phosgene under certain conditions. Contemporary studies focus on its behavior in the environment, atmospheric degradation mechanisms, as well as the impact on industrial health and safety. Understanding the chemical composition and physical properties of chloroform remains essential for risk assessment and its responsible management in modern applications, in the context of the transition to safer solvents and sustainable practices.

Pages:135-136
How to cite this article:
Ioana Stanciu "Composition determined by IR spectroscopy of chloroform". International Journal of Pharmaceutical Science and Research, Vol 11, Issue 1, 2026, Pages 135-136
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