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International Journal of
Pharmaceutical Science and Research
ARCHIVES
VOL. 11, ISSUE 1 (2026)
Schizophyllum commune: A comprehensive review of its nutritional value, phytochemistry, and pharmacological activities
Authors
Harsha Vardhana M G, Dr. Suresha B S, Dr. T Balasubramanian
Abstract
Schizophyllum commune is a widely distributed edible basidiomycete mushroom recognized for its nutritional, medicinal, and therapeutic potential. It is commonly found on hardwood and bamboo substrates and is traditionally consumed in several Asian and African regions. Rich in proteins, carbohydrates, dietary fiber, vitamins, and essential minerals, S. commune serves as an important dietary supplement, especially in developing countries. Phytochemical investigations reveal the presence of bioactive compounds such as alkaloids, flavonoids, phenolics, saponins, tannins, terpenoids, and polysaccharides, which contribute to its diverse biological activities. Numerous studies have demonstrated its antioxidant, antimicrobial, antifungal, antiviral, antitumor, anticancer, anti-inflammatory, antidiabetic, hepatoprotective, neuroprotective, and immunomodulatory properties. Schizophyllan, a major polysaccharide component, plays a crucial role in immune modulation and anticancer activity. Additionally, S. commune exhibits acetylcholinesterase inhibitory effects, highlighting its potential in managing neurodegenerative disorders. Traditional uses, combined with modern scientific evidence, emphasize its significance in functional food and pharmaceutical applications. This review compiles information on taxonomy, morphology, phytochemistry, nutritional composition, and pharmacological activities of S. commune, aiming to support further research and promote its utilization as a natural source of therapeutic agents and nutraceutical products.
Pages:97-102
How to cite this article:
Harsha Vardhana M G, Dr. Suresha B S, Dr. T Balasubramanian "<i>Schizophyllum commune</i>: A comprehensive review of its nutritional value, phytochemistry, and pharmacological activities". International Journal of Pharmaceutical Science and Research, Vol 11, Issue 1, 2026, Pages 97-102
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