ARCHIVES
VOL. 11, ISSUE 1 (2026)
A systematic review of phytochemical and pharmacological studies of Manilkara Zapota
Authors
Sheshadrigowda T V, Dr. T Balasubramanian, Dr. Suresha B S, Ahalya Devi K H
Abstract
Plants play a crucial role in human health,
providing essential nutrients, bioactive compounds, and therapeutic benefits. Manilkara
zapota (sapodilla), a member of the Sapotaceae family, is a tropical
fruit-bearing tree renowned for its nutritional and medicinal significance.
Distributed across Central America, the Caribbean, and tropical Asia, it
thrives in well-drained soils under moderate climatic conditions. Various parts
of M. zapota—including leaves, seeds, fruits, and bark—contain diverse
phytochemicals such as phenolic compounds, flavonoids, tannins, triterpenoids,
and glycosides, which underlie its broad spectrum of pharmacological
activities. Ethnopharmacological studies have documented its traditional use in
treating gastrointestinal disorders, fever, pain, and inflammatory conditions.
Modern pharmacological research supports these uses, demonstrating
anti-inflammatory, hypoglycemic, anti-lipidemic, analgesic, anticancer,
antimicrobial, antioxidant, antiulcer, neuroprotective, immunomodulatory, hepatoprotective,
anthelmintic, CNS depressant, and anti-pyretic activities. These effects are
attributed to its rich array of bioactive constituents, including quercetin,
myricetin, catechin, lupeol acetate, oleanolic acid, and zapotin. Collectively,
the evidence positions M. zapota as a promising natural source for
functional foods, nutraceuticals, and pharmaceutical development. This
review article provides more scientific information about the plant to the
researcher who carries the phytochemical and pharmacological screening of the
scientific plant.
Pages:60-66
How to cite this article:
Sheshadrigowda T V, Dr. T Balasubramanian, Dr. Suresha B S, Ahalya Devi K H "A systematic review of phytochemical and pharmacological studies of <i>Manilkara Zapota</i>". International Journal of Pharmaceutical Science and Research, Vol 11, Issue 1, 2026, Pages 60-66
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