Mesua ferrea is a rare plant used in India and several parts of world for its potential medicinal and several other properties. Mesua ferrea is a rich source of secondary metabolites which are having multiple health promoting benefits. The seed oil is helpful in various skin diseases and is a useful analgesic. The phytochemical screening confirms the presence of phenyl coumarins, xanthones, triterpenoids, and flavanoids as main constituents of the plant. From the recent studies it has been proved that Mesua ferrea is having multiple health promoting benefits including antioxidant, antimicrobial, immunomodulatory, antiarthritis, water disinfectant properties, anti-inflammatory activity, anticancer activities and others. The seed oil of Mesua ferrea shows various pharmacological activities like antioxidant activity, antimicrobial activity, immunomodulatory activity, antiarthritis activity, water disinfectant properties and anti-inflammatory activity. The pharmacological activities are due to the presence of phenolic compounds, essential oil, xanthones and coumarines present within the seed of this plant. Apart from medicinal uses it is also being used as biofuel, pharmacological excipients, biolubricant, polymer industry, painting, as a firewood and substitute for gasoline etc. Overall Mesua ferrea exhibits various uses and important application which can act as gift for curing various disease and disorder.