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VOL. 9, ISSUE 2 (2024)
Biodegradable polymers in sustained drug delivery systems
Authors
Mostafa AM Osman
Abstract
The field of drug delivery has witnessed
significant advancements with the development of biodegradable polymers,
offering a promising avenue for sustained and controlled release of therapeutic
agents. This abstract provides an overview of the key concepts and advancements
in utilizing biodegradable polymers for sustained drug delivery systems.
Biodegradable polymers, derived from natural or synthetic sources, have gained
prominence due to their ability to undergo enzymatic or chemical degradation
into non-toxic byproducts. This characteristic is particularly advantageous in
drug delivery applications as it addresses concerns related to toxicity and
potential side effects associated with long-term drug exposure. The sustained
drug delivery systems discussed in this abstract aim to achieve controlled
release kinetics, minimizing fluctuations in drug concentration and enhancing therapeutic
efficacy. Biodegradable polymers such as poly (lactic-co-glycolic acid) (PLGA),
polycaprolactone (PCL), and chitosan have demonstrated exceptional
biocompatibility and tunable degradation rates, making them suitable candidates
for various drug delivery applications. The incorporation of biodegradable
polymers in drug delivery systems allows for the formulation of implants,
microparticles, nanoparticles, and hydrogels. These formulations offer tailored
release profiles, enabling prolonged drug release over extended periods. The
choice of polymer, formulation method, and drug loading techniques plays a
crucial role in determining the release kinetics and overall performance of the
delivery system.
Pages:10-14
How to cite this article:
Mostafa AM Osman "Biodegradable polymers in sustained drug delivery systems". International Journal of Pharmaceutical Science and Research, Vol 9, Issue 2, 2024, Pages 10-14
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