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VOL. 8, ISSUE 3 (2023)
A review on formulation development and evaluation of self emulsifying drug delivery system of furosemide
Authors
Komal Devi, Shalini Sharma
Abstract
Furosemide is a highly
water-soluble diuretic used to treat conditions such as hypertension, edessma,
and congestive heart failure. Self-emulsifying drug delivery systems (SEDDS)
have been developed to improve drug solubility and absorption. This paper
presents an evaluation of SEDDS of furosemide through a review of relevant
literature. The studies reviewed demonstrate that SEDDS formulations
significantly improve the solubility of furosemide, enhance its
bioavailability, and exhibit improved pharmacokinetic properties compared to
conventional dosage forms. Additionally, SEDDS of furosemide have been found to
be easier to administer and swallow, potentially improving patient compliance.
These findings suggest that SEDDS may be a promising drug delivery system for
furosemide and other highly water-soluble drugs. Future research directions may
include exploring the effects of SEDDS on the stability and shelf-life of
furosemide formulations.
Pages:33-36
How to cite this article:
Komal Devi, Shalini Sharma "A review on formulation development and evaluation of self emulsifying drug delivery system of furosemide". International Journal of Pharmaceutical Science and Research, Vol 8, Issue 3, 2023, Pages 33-36
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