Stevia rebaudiana is more effective for renal function, because it contains a significant amount of sweet substances, a South American power station is seeing an increase in agriculture on a worldwide scale. Steviol saponins, that are respectively 250 and three hundred good interactions than carbohydrate, are the major cause of stevia's sweetness. Despite the advantages of Stevia derive over sugar and sweeteners being funded by various studies, it's still not a very prevalent sugar substitute. Recent research on the biological effects of S. rebaudiana extract as well as its personal flavonoid, including their potential to reduce cardiac output, keep improving renal function, and fight diseases like cancer, is explained in this review. There is also conversation of the toxic effects and possible side effects of stevia.