One of the most nutrient-dense cucurbit vegetables is the pointed gourd (Trichosanthes dioica Roxb.), which enjoys a prized spot in the Indian market during the warm and wet months. Fruits are easily digested and diuretic in nature, and they have some medical benefits due to their high protein and vitamin A content. Many reports are also available on their usefulness in decreasing blood sugar and serum triglycerides. The goal of the current study is to examine and assess the anthelmintic efficacy of a methanolic extract of Trichosanthes diocia leaf tissue. Different extracts and powdered material were subjected to chemical testing, which revealed the presence of proteins, amino acids, phytosterol and steroid, alkaloids, and flavonoids. Using albendazole as a reference, the various extracts were examined for their anthelmintic action at a concentration of 1,2,5, and it was discovered that methanol extracts had the greatest impact.