International Journal of Pharmaceutical Science and Research

Authors
Ragisha Francis, Mrunal K Shirsat

Abstract
The underlying causes of diabetes complications are protein glycosylation, oxidation, and changes in enzyme activity, all of which are brought on by hyperglycemia. Diabetic Nephropathy remains a major cause of morbidity and mortality in patients suffering from renal dysfunction. In this study, the ethanolic extract of Mollugo cerviana was tested for its ability to protect rats' kidneys against streptozotocin (STZ)-induced diabetic nephropathy. The oldest method of treating various diseases used by humans is the use of ethno-medicinal plants. The evaluation of medicinal plants' benefits and safety has expanded quickly along with the interest in their use. A significant decrease in blood glucose, urea, and creatinine was observed after treatment with Mollugo cerviana ethanolic extract at doses of 250 mg/body weight and 500 mg/body weight, along with an improvement in the electrolyte balance.