Colostrum is initial milk, highly nutritive secreted by mammals following parturition. The physiochemical property of colostrum is highly dynamic and variable. It is recommended to neonates must ingest colostrum for developing the passive immunity. The placental structure and transfer of immunity in utero, ingestion of colostrum after birth also confers provide additional protection by binding to the intestinal receptor which could otherwise be bound by the bacteria moreover, the adequate quantity colostrums can be reduce the neonatal death mortality the strong strength then immunity and increase animal life span but the delaying intake of colostrum in dairy calves can causes decreased transport of both immunoglobulin’s and fat soluble vitamins. In this article understanding the composition of colostrums, i.e. fat, proteins, lactose oligosaccharide, vitamins, minerals, growth factor, and nucleotide and its benefits to health of animals.