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VOL. 7, ISSUE 1 (2022)
Antianaemic effect of lyophilized red beetroots (Beta vulgaris L.) juice on anaemic rats induced by phenyl hydrazine
Authors
Haneen H Mouminah, Maha A Althaiban
Abstract
Anti-anaemic effect of lyophilized red beet juice in anemia rats were induced rats by phenyl hydrazine at the dose of 40 mg / kg / day for two days were evaluated. Forty (40) Wister albino male and female rats weighing between 100-150g. Groups B, C, D and E were injected twice into the intraperitoneally for two days with 40 mg / kg of phenyl hydrazine hydrochloride induce anemia in the rats, while group one served as a healthy rats without anemia. Group A rats without anemia were treated with 0.5ml of normal saline, Group B served as aneamic rats treated with 0.5ml of normal saline, Group C rats with anemia was treated with 50 mg/kg body weight of lyophilized red beet juice, Group D rats with anemia was treated with 100 mg/kg body weight of lyophilized red beet juice. Group E served as anemia rats was treated with 150 mg/kg body weight of lyophilized red beet juice. The feeding lasted for 21days after which the blood samples were collected from each rats via the ocular region for analysis. The parameters analyzed were packed cell volume (PCV), white blood cell (WBC), red blood cell (RBC) and hemoglobin (HB) concentrations. From the results of present work indicate that, the aneamic rats untreated with lyophilized red beet juice (group B) showed were decreased in hemoglobin concentration, Packed Cell Volume (PCV), red blood cells count (RBC) and increased in white blood count (WBC mm-3/L) compared with healthy rats group A after 7, 14 and 21 days respectively. The aneamic rats for group C, group D and group E were treated with lyophilized red beet juice orally at 50,100 and 150 mg / kg of body weight per day for three weeks were increased in hemoglobin concentration, Packed Cell Volume (PCV), red blood cells count (RBC) and decreased in white blood count (WBC) compared with aneamic rats untreated with lyophilized red beet juice (group B) respectively. Treated with lyophilized red beet juice for groups C, D and E were improved. The results of this study showed that lyophilized red beet juice improved the Haematological parameters of the treated rats thereby increasing the hemoglobin (Hb), packed cell volume (PCV) and red blood cell (RBC) levels of the rats. This is suggestive that lyophilized red beet juice may be implored in the treatment of anaemia.
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Pages:1-6
How to cite this article:
Haneen H Mouminah, Maha A Althaiban "Antianaemic effect of lyophilized red beetroots<em> (Beta vulgaris L.) </em>juice on anaemic rats induced by phenyl hydrazine ". International Journal of Pharmaceutical Science and Research, Vol 7, Issue 1, 2022, Pages 1-6
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