International Journal of Pharmaceutical Science and Research

Authors
Abdullah Osman Kocak, Sultan Tuna Akgol Gur, Ilker Akbas, Zeynep Cakir

Abstract
Introduction: Hemorrhoids are mucosal cushions around the anus that contain vascular tangles. It is a disease caused by swelling and displacement of these cushions due to various reasons, causing bleeding, pain, itching and discomfort in the person. According to researches, more than 3/4 of people are suffering from hemorrhoids at some point in their lives, and about half of those over age of 50 people need treatment.The aim of our study is to investigate the efficacy of Memethol® Barrier Spray on hemorrhoidal symptoms in patients admitted to the emergency department. Materials and Methods: Patients admitted to the emergency department with hemorrhoidal symptoms were included in the study. Patients were randomized into two groups by using a simple computer program. One group was designated as a study group and both IV dexketoprofen and Memethol® Barrier Spray are applied on this first group, in another hand the second group was designated as control group and only IV dexketoprofen was applied.The patients were asked to evaluate the pain, itching and discomfort in the rectal area by appraising between 0-10 points with visual analog scale at the beginning, 6th hour and 24th hour. Results: When the inclusion and exclusion criteria were applied on our study, 44 patients in the study group and 54 patients in the control group complete the study. Although both treatment methods were effective on hemorrhoidal symptoms, statistically Memethol® Barrier Spray was found more effective than IV dextroprofen. Conclusion: In our study, Memethol® Barrier Spray was found more effective than Dexketoprofen in pain reduction, itching and rectal discomfort in patients admitted to the emergency department with hemorrhoidal symptoms.