International Journal of Pharmaceutical Science and Research

Authors
Sharma Sheetal, Chauhan Lalita, Thakur Prerna, Dr. Arti R Thakkar

Abstract
The research project was aimed to developed and evaluated the anti-aging herbal topical formulation. The extracts of Aloe vera and Papaya fruit has been used in the formulation to improve as well synergize the cosmetic properties compared to individual extracts and evaluated for the several parameters like pH, spreadability, Total antioxidant activity, viscosity, in vitro drug release. The cream prepared from Aloe vera and Papaya fruit extract showed significantly better anti-aging efficacy as compared to the marketed formulation. The formulation was an ideal oil-in-water cream with good consistency, smooth and shining texture, good stability and may prove to be an anti-aging preparation and can be used for retarding the symptoms of ageing and showing skin-renewal activity. The optimized F9 formulation showed 62.34% (Aloe vera) and 64.56% (Papaya fruit) cumulative percent release. Thus, the research successfully exploited the use of herbal extracts like Aloe vera and Papaya fruit and antioxidant effect of the extracts was observed which is necessary to treat ageing signs. The developed cream was found with positive results of every evaluation parameter, which is necessary for a good formulation.