One of the most complex and challenging situations facing today’s pharmaceutical industry is patient medication adherence and compliance. This puzzling and multifaceted issue has been the subject of debate in the industry for many years, with various companies revamping strategies to encourage patients to better observe their medication schedules. However, patient adherence and compliance has proven to involve more than just the pharmaceutical companies developing the drugs. Many stakeholders need to actively participate in developing a solution. Although this is often the case, in a number of situations, the physician and pharmacist have not provided the patient with adequate instructions or have not presented the instructions in such a manner that the patient understands them. Nothing should be taken for granted regarding the patient’s understanding of how to use medication, and appropriate steps must be taken to provide patients with the information and counseling necessary to use their medications as effectively and as safely as possible. 20% to 30% of new prescriptions are never filled at the pharmacy. Medication is not taken as prescribed 50% of the time. For patients prescribed medications for chronic diseases, after six months, the majority take less medication than prescribed or stop the medication altogether. There are both federal and state laws that make using or sharing prescription drugs illegal. If someone take a pill that was prescribed to someone else or give that pill to another person, not only is it against the law, it's extremely dangerous.