The herbal toothpaste is prepared by using herbal extract cinnamon, neem, babul, guava and the other ingredient calcium carbonate, sodium lauryl sulphate, glycerin, gum tragacanth, water, saccharin, flavor and preservative. The herbal extract gives antimicrobial and antiinflametry activity and prevent and reducing the tooth decay, dental caries and given to freshness of mouth. The formulated herbal toothpaste is compare with marketed toothpaste they gives beneficial action and safety. The observation are found to be from physical examination appearance, spread ability, relevant density, viscosity, pH, homogenecity, foam ability, determination of moisture and volatile matter, antibacterial activity and Extrudability. The herbal toothpaste is no side effect and they prevent dental caries and dental disease.