International Journal of Pharmaceutical Science and Research

International Journal of Pharmaceutical Science and Research


International Journal of Pharmaceutical Science and Research
International Journal of Pharmaceutical Science and Research
Vol. 1, Issue 4 (2016)

Microspheres for colon targeted drug delivery: A comprehensive review


Dinesh Kumar, Kamal Saroha, Gourav Goyal, Deepika Yadav, Ashima Sorout, Surender Verma

Colon targeting is a comparatively new approach for the localized delivery of drugs to obtain maximum possible output for the treatment of ailments. In order to target a drug inside the body it is required to be in the form of a dosage form. Various conventional dosage forms are there to target drugs to the colon but they don’t prove to be efficient in the controlled and sustained release. Different Novel drug delivery systems are developed in order to overcome the disadvantages of conventional dosage forms such as liposomes, microspheres, nanoparticles etc. Microsphere is the novel drug delivery system having the particle size of less than 200µm. The materials used, polymers used and method of preparation have a characteristic influence on the therapeutic efficacy of microspheres. This review targets the various advantages of microspheres over the conventional dosage forms for colon targeting of drugs, their different method of preparation, properties of microspheres which are deciding factors for the efficient delivery of drugs and their evaluation techniques used. Microspheres are not only beneficial in sustained drug delivery but also serve as an efficient tool for localized therapy.
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How to cite this article:
Dinesh Kumar, Kamal Saroha, Gourav Goyal, Deepika Yadav, Ashima Sorout, Surender Verma. Microspheres for colon targeted drug delivery: A comprehensive review. International Journal of Pharmaceutical Science and Research, Volume 1, Issue 4, 2016, Pages 39-45
International Journal of Pharmaceutical Science and Research