International Journal of Pharmaceutical Science and Research

Authors
Kalaiarasi V, Johnson M, Janakiraman N, Sivaraman A

Abstract
The present study was aimed to find out the phytochemical composition and antibacterial potential of Peperomia pellucida (L.) H.B.K. against the fish pathogens. Preliminary phytochemical constituents of P. pellucida were analysed using the standard procedure described by Harborne. The bacterial pathogens Bacillus subtilis, Escherichia coli and Pseudomonas aeruginosa were isolated from diseased tilapia and their identity was confirmed using the standard procedure. Antibacterial screening was carried out by agar well diffusion method against the selected pathogens viz., Escherichia coli, Bacillus subtilis and Pseudomonas aeruginosa. Phytochemical screening revealed the presence of alkaloids, steroids and phenolic groups. Among the five different extracts, the ethanolic extract exhibited maximum degree of inhibition followed by acetone and chloroform. Ethanolic extract showed the maximum degree of zone of inhibition against P. aeruginosa (14 mm) followed by B. subtilis (13 mm) and E. coli (10 mm). The present study results may direct to the discovery of new antibacterial compounds for treating various infections.