The main objective of the study was the formulation and evaluation of bio-adhesive flexy films to deliver nanosized rosuvastatin. The bio-flexy films were aimed to deliver through the nabhi. A novel bio-film former was isolated from the seeds of a natural edible source, Cleome viscosa. The isolated biopolymer was screened for its film forming ability by preparing bi-flexy films of the isolated biopolymer by solvent casting method. Five formulations (RC1-RC5) were prepared by varying the polymer: drug ratios (1:1, 1:2, 1:3, 1:4, 1:5) by solvent casting method. Rosuvastatin was nanosized, and used as the model drug. The formulated bio-flexy films were tested for surface pH, thickness, weight variation, content uniformity, folding endurance. In-vitro study showed that formulation RC2 (1:2) was the best formulation having R² value 0.9286, and Higuchi-Matrix as best fit model. The conclusion was drawn that the isolated biopolymer has good film forming capacity, and can be utilised for designing various pharmaceutical formulations.