International Journal of Pharmaceutical Science and Research

International Journal of Pharmaceutical Science and Research

ISSN: 2455-4685

Vol. 4, Issue 1 (2019)

Quality assessment of selected marketed irbesartan 300mg tablets brands in Iraq

Author(s): Asmaa Abdelaziz Bayoumi
Abstract: Objective: The goal of this study was to assess the quality of some selected irbesartan products in community pharmacies in Iraq. Methods: Different parameters of quality control of pharmaceutical products can guarantee the quality and bioavailability and optimal therapeutic activity. Used quality control parameters, i.e., the variation of weight, friability, content uniformity, disintegration time and dissolution profiles were assessed in vitro. Results: The weight range of Aprovel 300mg was in range of 0.505 g-0.523g while Converium weight range of 0.594-603 g and Gizlan 300 mg weight range was of 0.495-0.507g. Conclusion: The results showed that all products fulfill the given specification of Pharmacopeia (USP-NF) except Converium which its dissolution rate was less than % in USP (80% after 20 min).
Pages: 53-55  |  198 Views  102 Downloads
International Journal of Pharmaceutical Science and Research
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