Vol. 2, Issue 4 (2017)
Synthesis, characterization and biological screening of novel pyrazolone derivatives for certain pharmacological activities
Author(s): Mathew George, Lincy Joseph, Ansa Thomas
Abstract: Pyrazolone derivatives are prepared by condensation reaction of ethyl etoacetate, hydrazine hydrate and substituted aromatic aldehyde in alcohol. All synthesized compounds were characterized by physicochemical properties, IR, NMR etc. The compounds are screened for different biological activities like antimicrobial, anti-inflammatory, analgesic, anticonvulsant, and anti-diabetic activities.