Vol. 1, Issue 4 (2016)
Blue brain: Novel tool of drug discovery for brain disorders
Author(s): Radha Pal, Sonam Singh, Raj K Prasad
Abstract: Blue brain is the name of the world’s first virtual brain. That means a machine can function as human brain. Today scientists are in research to create an artificial brain that can think, response, take decision, and keep anything in memory. Today, there are only very few brain disorders whose causes are fully understood and very few drugs whose mechanism of action is known or that offer more than symptomatic relief. The Blue brain project will offer new opportunities for clinicians and for researchers. Groups working in the project have already collected and analyzed very large volumes of imaging data from hospitals, and have used informatics based analysis to achieve highly effective early diagnosis of brain disease. The Blue brain project will develop this work, which we expect to yield clinically useful results in the relatively short term. In a medium-term perspective, the Blue brain project simulation platform will make it possible to explore hypotheses of causation for brain diseases, and begin simulating the effects of drug candidates. Simulation-based prototypes will enormously facilitate the development of neuroprosthetic devices. These new possibilities will shorten design cycles, lower costs and improve prospects for the development of effective treatments. To allow effective drug simulation, the project will make an important effort to explore and simulate molecular level mechanisms.