International Journal of Pharmaceutical Science and Research

International Journal of Pharmaceutical Science and Research

ISSN: 2455-4685

Vol. 1, Issue 4 (2016)

Synergistic Antioxidant and Anti-bacterial Activities of Croton zambesicus Müll.-Arg. (Euphorbiaceae) Leptoderris micrantha Dunn (Fabaceae) and Carpolobia lutea G. Don (Polygalaceae)

Author(s): Famobuwa OE, Oloyede HO, Bello IJ
Abstract: The objective of this research was to evaluate, comparatively, the anti-oxidant and anti-bacteria properties of the mixture and the individual plants to ascertain if there is need for the continuous use of the herbal mixture as a pro-fertility therapy. The standard methods used to investigate the antioxidant activity were the standard methods of 1, 1-diphenyl-2-picrylhydrazyl and Ferric Reducing Antioxidant Property (FRAP). Anti-bacterial activity was evaluated by the Agar well Diffusion method. The herbal mixture performed better as an anti-oxidant agent than its constituent herbal plants. As an antibacterial agent, it compared favourably with C. zambesicus but better than L. micrantha and C. lutea. The herbal mixture had a better antioxidant activity than any of the constituent herbal plants while C. zambesicus performed slightly better than the mixture and L. micrantha compared favourably with the mixture as anti-bacterial agents. Based on these findings, its use should be encouraged as a pro-fertility herbal therapy.
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International Journal of Pharmaceutical Science and Research
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